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Selected Publications 2021

  • Chan EW, Lao KSJ, Lam L, Tsui SH, Lui CT, Wong CP, Graham CA, Cheng CH, Chung TS, Lam HF, Ting SM, Knott JC, Taylor DM, Kong DCM, Leung LP, Wong ICK. Intramuscular midazolam, olanzapine, or haloperidol for the management of acute agitation: A multi-centre, double-blind, randomised clinical trial. EClinicalMedicine. 2021 Feb 11;32:100751. https://doi.org/10.1016/j.eclinm.2021.100751 . PMID: 33681744; PMCID: PMC7910711.
  • Cheung ACK, Yan, BTH, Sung HTT. An uncommon structure detected by point-of-care ultrasound. Vis J Emerg Med 2022 Jan; 26: 101203. https://doi.org/10.1016/j.visj.2021.101203 
  • Cheung ACK, Lam RPK, Fok PWF, Ng EPH, Chaang VK, Rainer TH. Predictors for in-flight medical interventions during helicopter interfacility transport in Hong Kong. Hong Kong Journal of Emergency Medicine. 2021 Jul 8;1-9 https://doi.org/10.1177/10249079211030110 
  • Choudhry M, Edwards M, Cooper A, Anderson P, Carson-Stevens A, Cooke M, Dale J, Hibbert P, Hughes T, Porter A, Rainer T, Siriwardena AN, Edwards A. Senior clinical and business managers' perspectives on the influence of different funding mechanisms, and barriers and enablers to implementing models of employing General Practitioners in or alongside emergency departments: Qualitative study. Health Policy. 2021 Apr;125(4):482-488. https://doi.org/10.1016/j.healthpol.2020.11.016 . Epub 2021 Jan 22. PMID: 33526280.
  • Du R, Tsougenis ED, Ho JWK, Chan JKY, Chiu KWH, Fang BXH, Ng MY, Leung ST, Lo CSY, Wong HF, Lam HS, Chiu LJ, So TY, Wong KT, Wong YCI, Yu K, Yeung YC, Chik T, Pang JWK, Wai AK, Kuo MD, Lam TPW, Khong PL, Cheung NT, Vardhanabhuti V. Machine learning application for the prediction of SARS-CoV-2 infection using blood tests and chest radiograph. Sci Rep. 2021 Jul 9;11(1):14250. https://doi.org/10.1038/s41598-021-93719-2 . PMID: 34244563; PMCID: PMC8270945.
  • Edwards M, Cooper A, Hughes T, Davies F, Sherlock R, Anderson P, Evans B, Carson-Stevens A, Cooke M, Dale J, Hibbert P, Harrington B, Hepburn J, Porter A, Rainer T, Siriwardena AN, Snooks H, Edwards A. A classification of primary care streaming pathways in UK emergency departments: Findings from a multi-methods study comprising cross-sectional survey; site visits with observations, semi-structured and informal interviews. Int Emerg Nurs. 2021 Apr 17;56:101000. https://doi.org/10.1016/j.ienj.2021.101000 . Epub ahead of print. PMID: 33878641.
  • Ganotice F.J.A., Fan K.H.K., Ng L.H., Tsoi H.S., Wai K.C.A., Worsley A.J., Lin X. and Tipoe G.L., The short version of students' perceptions of interprofessional clinical education-revised (SPICE-R3): a confirmatory factor analysis, Journal of Interprofessional Care. 2021, 28,1-9. http://dx.doi.org/10.1080/13561820.2021.1879751  (Publication No. : 322398; Weighting : 0.1250; Publication Date: Apr 2021)
  • Hung KKC, Lam RPK, Lui CT. Bringing sepsis care back to the emergency department: New prognostic tools and extended role of emergency physicians. Hong Kong J Emerg Med 2021;28(4):197-8. https://doi.org/10.1177/10249079211019870 .
  • Hung KKC, Rainer TH, Yeung JHH, Cheung C, Leung Y, Leung LY, Chong M, Ho HF, Tsui KL, Cheung NK, Graham C. Seven-year excess mortality, functional outcome and health status after trauma in Hong Kong. Eur J Trauma Emerg Surg. 2021 Jun 4. https://doi.org/10.1007/s00068-021-01714-z . Epub ahead of print. PMID: 34086062.
  • Jiang H, Mao H, Lu H, Lin P, Garry W, Lu H, Yang G, Rainer TH, Chen X. Machine learning-based models to support decision-making in emergency department triage for patients with suspected cardiovascular disease. Int J Med Inform. 2021 Jan;145:104326. https://doi.org/10.1016/j.ijmedinf.2020.104326 . Epub 2020 Nov 3. PMID: 33197878.
  • Jones J, Allen S, Davies J, Driscoll T, Ellis G, Fegan G, Foster T, Francis N, Islam S, Morgan M, Nanayakkara PWB, Perkins GD, Porter A, Rainer T, Ricketts S, Sewell B, Shanahan T, Smith FG, Smyth MA, Snooks H, Moore C. Randomised feasibility study of prehospital recognition and antibiotics for emergency patients with sepsis (PhRASe). Sci Rep. 2021 Sep 20;11(1):18586. https://doi.org/10.1038/s41598-021-97979-w . PMID: 34545117; PMCID: PMC8452688.
  • Kwok CYT, Wong MS, Chan KL, Kwan MP, Nichol JE, Liu CH, Wong JYH, Wai AKC, Chan LWC, Xu Y, Li H, Huang J, Kan Z. Spatial analysis of the impact of urban geometry and socio-demographic characteristics on COVID-19, a study in Hong Kong. Sci Total Environ. 2021 Apr 10;764:144455. https://doi.org/10.1016/j.scitotenv.2020.144455 . Epub 2020 Dec 16. PMID: 33418356; PMCID: PMC7738937
  • Lam P.K., Chan K.L., Cheung C.K.A., Wong K.W., Lau E.H.Y., Chen L., Chaang V.K. and Woo P.C.Y., The limited value of triage vital signs in predicting influenza infection in children aged 5 years and under in the emergency department, Medicine. 2021, 100, e27707. http://dx.doi.org/10.1097/MD.0000000000027707   
  • Lam RPK, Lau EHY, Yip WL, Leung JKS, Tsui MSH. Traditional Chinese medicine poisoning in the emergency departments in Hong Kong: Trend, clinical presentation and predictors for poor outcome. World J Emerg Med 2021; 12(2):143-150. https://doi.org/10.5847/wjem.j.1920-8642.2021.02.010 .
  • Latham J, Hicks Y, Yang X, Setchi R, Rainer T. Stable Automatic Envelope Estimation for Noisy Doppler Ultrasound. IEEE Trans Ultrason Ferroelectr Freq Control. 2021 Mar;68(3):465-481. https://doi.org/10.1109/TUFFC.2020.3011823 . Epub 2021 Feb 25. PMID: 32746225.
  • Law CY, Leung SC, Loong F, Ling TK, Wong KC, Lau KC, Tsui SHM, Lai CL and Lam CW.  Serum ceruloplasmin monitoring in a case of silver intoxication due to intravenous silver infusion. Clinical Toxicology. 2021, 1-4. http://dx.doi.org/10.1080/15563650.2021.1919692 
  • Leung S.K. and Wai K.C.A., Low rates of liver injury in edoxaban users: Evidence from a territory-wide observational cohort study, Clinical Cardiology. 2021, 44, 886-889. https://doi.org/10.1002/clc.23570
  • Leung SC (first and corresponding author), Tsui SH. Safe use of chemical restraint for agitated and violent adult patients. Hong Kong Medical Diary 2021;26(10):26-31. (Oct 2021)
  • Mui JV, Zhou J, Lee S, Leung KS, Lee TT, Chou OH, Tsang SL, Wai AK, Liu T, Wong WT, Chang C. Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitors vs. Dipeptidyl Peptidase-4 (DPP4) Inhibitors for New-Onset Dementia: A Propensity Score-Matched Population-Based Study With Competing Risk Analysis. Front. Cardiovasc. Med. 8: 747620. https://doi.org/10.3389/fcvm.2021.747620 . 2021 Oct 21.
  • Phillips AO, Foxwell DA, Pradhan S, Zouwail S, Rainer TH. Derivation of a prediction model for emergency department acute kidney injury. Am J Emerg Med. 2021 Feb;40:64-69. https://doi.org/10.1016/j.ajem.2020.12.017 . Epub 2020 Dec 13. PMID: 33348226.
  • Tse G., Zhou J., Lee S., Wong W.T., Li X., Liu T., Cao Z., Zeng D.D., Wai K.C.A., Wong I.C.K., Cheung B.M.Y. and Zhang Q., Relationship between angiotensin-converting enzyme inhibitors or angiotensin receptor blockers and COVID-19 incidence or severe disease, Journal of Hypertension. 2021, Publish Ahead of Print. http://dx.doi.org/10.1097/HJH.0000000000002866 (Publication No. : 322829; Weighting : 0.0833; Publication Date: Apr 2021)
  • Wai K.C.A., Wong C.K.H., Wong J.Y.H., Xiong X.I., Chu C.K., Wong M.S., Tsui S.H.M. and Rainer T.H., Changes in emergency department visits, diagnostic groups and 28-day mortality associated with the COVID-19 pandemic: a territory-wide, retrospective, cohort study, Annals of Emergency Medicine. 2021. https://doi.org/10.1016/j.annemergmed.2021.09.424
  • Wong KW, Lam RPK, Sin WC, Irwin MG, Rainer TH. Comparison of the Efficiency and Usability of Aerosol Box and Intubation Tent on Intubation of a Manikin Using Personal Protective Equipment: A Randomized Crossover Study. J Emerg Med. 2021 Sep 9:S0736-4679(21)00556-4.  https://www.jem-journal.com/article/S0736-4679(21)00556-4/fulltext. Epub ahead of print. PMID: 34511295.
  • Wong J.Y.H., Wai K.C.A., Wang M.P., Lee J.J.J., Li M., Kwok Y.Y., Wong C.K.H. and Choi A.W.M., Impact of COVID-19 on child maltreatment: Income instability and parenting issues , International Journal of Environmental Research and Public Health. 2021, 18(4), 1501. http://dx.doi.org/10.3390/ijerph18041501  (Publication No. : 321295; Weighting : 0.1250; Publication Date: Feb 2021)
  • Xiong X, Wai AKC, Wong JYH, Tang EHM, Chu OCK, Wong CKH, Rainer TH. Impact of varying wave periods of COVID-19 on in-hospital mortality and length of stay for admission through emergency department: A territory-wide observational cohort study. Influenza Other Respir Viruses. 2022 Mar;16(2):193-203. https://doi.org/10.1111/irv.12919 . Epub 2021 Oct 13. PMID: 34643047; PMCID: PMC8653231.
  • Zhou J., Lee S., Guo C.L., Chang C., Liu T., Leung S.K., Wai K.C.A., Cheung B.M.Y., Tse G. and Zhang Q., Anticoagulant or antiplatelet use and severe COVID-19 disease: A propensity score-matched territory-wide study, Pharmacological Research. 2021, 105473. http://dx.doi.org/10.1016/j.phrs.2021.105473  (Publication No. : 321322; Weighting : 0.2000; Publication Date: Jan 2021)
  • Zhou J., Lee S., Wang X., Li Y., Wu W.K.K., Liu T., Cao Z., Zeng D.D., Leung S.K., Wai K.C.A., Wong I.C.K., Cheung B.M.Y., Zhang Q. and Tse G., Development of a multivariable prediction model for severe COVID-19 disease: a population-based study from Hong Kong, npj Digital Medicine. 2021, 4. http://dx.doi.org/10.1038/s41746-021-00433-4 (Publication Date: Dec 2021)
  • Zhou J, Lee S, Wong WT, Waleed KB, Leung KSK, Lee TTL, Wai AKC, Liu T, Chang C, Cheung BMY, Zhang Q, Tse G. Gender-specific clinical risk scores incorporating blood pressure variability for predicting incident dementia. J Am Med Inform Assoc. 2022 Jan 12;29(2):335-347. https://doi.org/10.1093/jamia/ocab173 . PMID: 34643701; PMCID: PMC8757295.
  • Zhou J., Tse G., Lee S., Liu T., Cao Z., Zeng D.D., Leung S.K., Wai K.C.A., Wong I.C.K., Cheung B.M.Y. and Zhang Q., Interaction effects between angiotensin‐converting enzyme inhibitors or angiotensin receptor blockers and steroid or antiviral therapies in COVID‐19: A population‐based study, Journal of Medical Virology. 2021, 93, 2635-2641. http://dx.doi.org/10.1002/jmv.26904  (Publication No. : 322828; Weighting : 0.1818; Publication Date: May 2021)